Flow cytometric detection of liposomal cytarabine in cerebrospinal fluid of patients treated with intrathecal chemotherapy

Alessandra Stacchini; Anna Demurtas; Sabrina Aliberti

doi:10.1002/cyto.b.21029

Flow cytometric detection of liposomal cytarabine in cerebrospinal fluid of patients treated with intrathecal chemotherapy

Cytometry B Clin Cytom. 2012 Sep;82(5):280-2. doi: 10.1002/cyto.b.21029. Epub 2012 Aug 6.

Authors

Alessandra Stacchini¹, Anna Demurtas, Sabrina Aliberti

Affiliation

¹ Department of Pathology, Flow cytometry unit, Molinette Hospital, Via Santena 7, 10126 Turin, Italy. astacchini@molinette.piemonte.it

PMID: 22539249
DOI: 10.1002/cyto.b.21029

Abstract

We report the unusual flow cytometric detection of liposomes in the cerebrospinal fluid of patients with aggressive non-Hodgkin's lymphoma and acute myeloid leukemia, treated with intrathecal liposomal cytarabine.

MeSH terms

Antimetabolites, Antineoplastic / administration & dosage
Antimetabolites, Antineoplastic / cerebrospinal fluid*
Cytarabine / administration & dosage
Cytarabine / cerebrospinal fluid*
Flow Cytometry
Humans
Injections, Spinal
Leukemia, Myeloid, Acute / cerebrospinal fluid*
Leukemia, Myeloid, Acute / drug therapy
Liposomes
Lymphoma, Non-Hodgkin / cerebrospinal fluid*
Lymphoma, Non-Hodgkin / drug therapy

Substances

Antimetabolites, Antineoplastic
Liposomes
Cytarabine