Serum galactomannan in cystic fibrosis patients colonized with Aspergillus species

Med Mycol. 2012 Aug;50(6):658-60. doi: 10.3109/13693786.2012.676739. Epub 2012 Apr 23.

Abstract

Cystic fibrosis patients are often colonized by Aspergillus species. Sera from 138 pediatric and adult cystic fibrosis patients were tested for the presence of galactomannan. All serum samples were negative for galactomannan and there was no difference among patients who were chronically, intermittently, and never colonized with Aspergillus.

MeSH terms

  • Adolescent
  • Adult
  • Antigens, Fungal / blood*
  • Aspergillosis / microbiology
  • Aspergillosis / pathology
  • Aspergillus fumigatus / isolation & purification*
  • Aspergillus fumigatus / pathogenicity
  • Child
  • Cystic Fibrosis / blood
  • Cystic Fibrosis / microbiology*
  • Female
  • Forced Expiratory Volume
  • Galactose / analogs & derivatives
  • Humans
  • Immunoenzyme Techniques / methods
  • Lung / microbiology
  • Lung / pathology
  • Male
  • Mannans / blood*
  • Middle Aged
  • Young Adult

Substances

  • Antigens, Fungal
  • Mannans
  • galactomannan
  • Galactose