Synthesis of cholic acid based calixpyrroles and porphyrins

Thu Huong Nguyen Thi; Lenka Cardová; Michaela Dvořáková; Dagmar Ročková; Pavel Drašar

doi:10.1016/j.steroids.2012.04.008

Synthesis of cholic acid based calixpyrroles and porphyrins

Steroids. 2012 Jul;77(8-9):858-63. doi: 10.1016/j.steroids.2012.04.008. Epub 2012 Apr 21.

Authors

Thu Huong Nguyen Thi¹, Lenka Cardová, Michaela Dvořáková, Dagmar Ročková, Pavel Drašar

Affiliation

¹ Department of Chemistry, Faculty of Natural Sciences, JE Purkyně University Ústí nad Labem, Ústí nad Labem, Czech Republic.

PMID: 22522238
DOI: 10.1016/j.steroids.2012.04.008

Abstract

New cholic acid based calix[4]pyrroles and porphyrins were prepared and their properties were studied. It was confirmed by spectral measurements that the superassembly of 5,15-bis(3α,7α,12α-trihydroxy-5β-cholan-24-yl)-10,20-diphenylporphyrin, the best candidate for this study from the conjugates prepared, may be influenced not only by the solvent mixture composition (polar/non-polar component ratio) but by time as well.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cholic Acid / chemistry*
Microwaves
Models, Molecular
Porphyrins / chemical synthesis*
Porphyrins / chemistry*
Pyrroles / chemical synthesis*
Pyrroles / chemistry*

Substances

Porphyrins
Pyrroles
Cholic Acid