Studies on the stage of action of lasalocid against Eimeria tenella and Eimeria acervulina in the chicken

Vet Parasitol. 1990 Oct;37(2):93-100. doi: 10.1016/0304-4017(90)90064-i.

Abstract

Broiler chickens in battery pens were either fed a diet containing 100 ppm lasalocid or no drug for 24 h prior to inoculation with sporulated oocysts of Eimeria tenella or Eimeria acervulina. Different groups of birds remained on medicated feed for 24, 48, 72, 96, 120 or 144 h after inoculation. Conversely, other groups started on an unmedicated diet, were given medicated feed at different times after oocyst inoculation. Starting lasalocid medication 24 h (E. tenella) or 48 h (E. acervulina) after inoculation reduced the lesions and improved the weight gain. There was no significant difference in performance of birds after withdrawal of the drug at 48 h (E. tenella) or 72 h (E. acervulina) and thereafter. Starting lasalocid medication at 96 or 120 h did not suppress but rather reduced oocyst production.

MeSH terms

  • Animals
  • Chickens / parasitology*
  • Coccidiosis / drug therapy
  • Coccidiosis / veterinary*
  • Eimeria / drug effects*
  • Lasalocid / pharmacology
  • Lasalocid / therapeutic use*
  • Poultry Diseases / drug therapy*
  • Weight Gain

Substances

  • Lasalocid