Exercise-training reduced blood pressure and improve placental vascularization in pregnant spontaneously hypertensive rats--pilot study

Fetal Pediatr Pathol. 2012 Dec;31(6):423-31. doi: 10.3109/15513815.2012.659535. Epub 2012 Apr 16.

Abstract

Assess the effects of exercise-training on resting arterial pressure and heart rate, placental fetuses morphologic alterations in pregnant spontaneously hypertensive rats (SHRs).Twenty SHRs and their respective control normotensive rats (WKY) were submitted or not to a swimming protocol during 9 weeks, resulting in four pregnant experimental groups: sedentary hypertensive (PSH), trained hypertensive (PTH), sedentary normotensive (PSN), and trained normotensive (PTN). Exercise-training by swimming attenuates arterial pressure in pregnant SHRs, and can contribute to an increase in the length of fetuses and the percentage of the vessels in the placenta.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Pressure / physiology*
  • Crown-Rump Length
  • Exercise Therapy*
  • Female
  • Fetal Weight
  • Heart Rate / physiology
  • Hypertension / physiopathology
  • Hypertension / therapy*
  • Neovascularization, Physiologic / physiology*
  • Physical Conditioning, Animal / physiology*
  • Placenta / blood supply*
  • Placenta / pathology
  • Pregnancy
  • Pregnancy Outcome
  • Rats
  • Rats, Inbred SHR
  • Rats, Inbred WKY
  • Swimming / physiology