The efficacy of self-expanding metal stents for colorectal obstruction with unresectable stage IVB colorectal cancer

Hepatogastroenterology. 2012 Nov-Dec;59(120):2472-6. doi: 10.5754/hge12139.

Abstract

Background/aims: Acute colorectal obstruction with stage IVB colorectal cancer has a poor prognosis and short life expectancy. The effectiveness of self-expanding metal stents (SEMS) has been demonstrated in colorectal cancer patients with obstruction. However, little is known about the palliative efficacy of stent placement inpatients with unresectable colorectal cancer.

Methodology: The medical records of patients who received SEMS for stage IVB colorectal cancer with acute colorectal obstruction between March 2004 and July 2010 were retrospectively reviewed. A total of 24 patients with unresectable Stage IVB colorectal cancer with acute colorectal obstruction were enrolled in this study.

Results: Twenty-four patients received SEMS placement during the study period. The mean age of the patients was 63.0 years (range 35-84 years). Fifteen patients were male and nine were female. The most common obstructive lesion was in the sigmoid colon (70.8%), including the sigmoid-descending and rectosigmoid junctions. Un-covered SEMS were used in 62.5% of patients. On the first attempt, the technical success rate of SEMS was 95.8%. The estimated duration of primary stent patency and overall survival periods after SEMS were 332.0 and 231.8 days, respectively.

Conclusions: SEMS insertion may be a useful therapeutic choice for acute colorectal obstruction in patients with unresectable stage IVB colorectal cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / mortality
  • Adenocarcinoma / pathology
  • Adult
  • Aged
  • Aged, 80 and over
  • Colonic Diseases / etiology
  • Colonic Diseases / mortality
  • Colonic Diseases / therapy*
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / mortality
  • Colonic Neoplasms / pathology
  • Colonoscopy / adverse effects
  • Colonoscopy / instrumentation*
  • Female
  • Humans
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / mortality
  • Intestinal Obstruction / therapy*
  • Kaplan-Meier Estimate
  • Male
  • Metals*
  • Middle Aged
  • Neoplasm Staging
  • Palliative Care
  • Prosthesis Design
  • Rectal Diseases / etiology
  • Rectal Diseases / mortality
  • Rectal Diseases / therapy*
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome

Substances

  • Metals