Abstract
Neuroendocrine gastroenteropancreatic tumors constitute a heterogeneous group of neoplasms, with the primary tumors being located in the gastric mucosa, pancreas, and small and large intestine. The development of a second primary malignancy in patients with these tumors is a well-described phenomenon, and the reported incidence ranges from 12% to 46%. The most common site of associated noncarcinoid malignancies is the gastrointestinal tract, which involves from 30% to 60% of the tumors. We report a case of concurrent colon carcinoma and two neuroendocrine tumors of the duodenum.
MeSH terms
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Adenocarcinoma / diagnosis*
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Carcinoma / diagnosis
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Cecal Neoplasms / diagnosis
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Chemotherapy, Adjuvant
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Colectomy
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Colonic Neoplasms / diagnosis
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Duodenal Neoplasms / diagnosis
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Fluorouracil / administration & dosage
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Gastrectomy
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Humans
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Immunohistochemistry
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Intestinal Neoplasms / diagnosis*
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Leucovorin / administration & dosage
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Male
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Meckel Diverticulum / diagnosis*
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Middle Aged
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Neoplasms, Multiple Primary / diagnosis*
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Neuroendocrine Tumors / diagnosis*
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Organoplatinum Compounds / administration & dosage
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Treatment Outcome
Substances
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Organoplatinum Compounds
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Leucovorin
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Fluorouracil