Chimeric antisense RNA derived from chromosomal translocation modulates target gene expression

Haematologica. 2012 Aug;97(8):1278-80. doi: 10.3324/haematol.2011.057869. Epub 2012 Apr 4.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amino Acid Sequence
  • Base Sequence
  • Chromosomes, Human, Pair 12
  • Chromosomes, Human, Pair 17
  • ETS Translocation Variant 6 Protein
  • Exons
  • Gene Expression Regulation, Neoplastic*
  • Gene Order
  • Humans
  • MAP Kinase Kinase Kinases / genetics
  • Male
  • Molecular Sequence Data
  • Myelodysplastic Syndromes / genetics*
  • Oncogene Proteins, Fusion / genetics*
  • Protein Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-ets / genetics
  • RNA, Antisense*
  • Repressor Proteins / genetics
  • Transcription, Genetic
  • Translocation, Genetic*

Substances

  • Oncogene Proteins, Fusion
  • Proto-Oncogene Proteins c-ets
  • RNA, Antisense
  • Repressor Proteins
  • Protein Serine-Threonine Kinases
  • TAO1 protein kinase
  • MAP Kinase Kinase Kinases