Biological correlates and predictors of insulin resistance among early adolescents

Ross J Bindler; Ruth C Bindler; Kenneth B Daratha

doi:10.1016/j.pedn.2012.03.022

Biological correlates and predictors of insulin resistance among early adolescents

J Pediatr Nurs. 2013 Jan;28(1):20-7. doi: 10.1016/j.pedn.2012.03.022. Epub 2012 Apr 5.

Authors

Ross J Bindler¹, Ruth C Bindler, Kenneth B Daratha

Affiliation

¹ Washington State University, College of Pharmacy, Spokane, WA, USA. bindler@wsu.edu

PMID: 22484110
DOI: 10.1016/j.pedn.2012.03.022

Abstract

Abnormal glucose metabolism is associated with obesity, insulin resistance (IR), and Type 2 diabetes mellitus. The purposes of this study were to describe anthropometric and laboratory markers of adolescents, examine correlates of IR, and test ability of anthropometric and laboratory markers to predict risk of exhibiting IR. A total of 150 early adolescents participated. Participants with obesity had increased IR, high-sensitivity C-reactive protein, triglycerides, and blood pressure. Waist circumference and triglycerides were predictive of IR. Multiple risk factors compound and lead to long-term health consequences among youth. Nurses can evaluate these factors to identify IR.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Adolescent
C-Reactive Protein / analysis
Cholesterol, HDL / blood
Female
Humans
Insulin Resistance* / physiology
Male
Obesity / prevention & control
Prevalence
Risk Factors
Triglycerides / blood
Waist Circumference*

Substances

Cholesterol, HDL
Triglycerides
C-Reactive Protein