Abstract
A combination of rolling circle amplification and nicking endonuclease-assisted nanoparticle amplification (NEANA) is used for the rapid, colorimetric detection of DNA. The integration of rolling circle amplification into the NEANA approach allows for detection of oligonucleotides with arbitrary sequences at ultralow concentrations.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Colorimetry / methods*
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DNA / analysis*
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DNA / chemistry
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Endonucleases / metabolism
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Escherichia coli / metabolism
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Gold / chemistry
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Metal Nanoparticles / chemistry
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Microscopy, Atomic Force
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Molecular Sequence Data
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Nanoparticles / chemistry*
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Nucleic Acid Amplification Techniques
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Nucleic Acid Hybridization
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Oligonucleotides / chemistry
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Sequence Homology, Nucleic Acid
Substances
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Oligonucleotides
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Gold
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DNA
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Endonucleases