The polyphenolic composition and antioxidant properties of selected red wines from Morocco were evaluated. All of the wines tested showed very similar anthocyanin and flavonol patterns: individual compound contents resulted generally higher in comparison to conventional wines. Samples revealed a higher reducing capacity than radical scavenging property and a good correlation between antioxidant activity and polyphenolic content values. Each wine exhibited not only a moderate to high natural preserving capacity but also potentially beneficial influence on human health.