Pharmacokinetic interaction between tacrolimus and amlodipine in a renal transplant child

Transplantation. 2012 Apr 15;93(7):e29-30. doi: 10.1097/TP.0b013e318249b180.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism
  • Amlodipine / therapeutic use*
  • Antihypertensive Agents / therapeutic use*
  • Child, Preschool
  • Cytochrome P-450 CYP3A / genetics
  • Cytochrome P-450 CYP3A / metabolism
  • Drug Interactions
  • Graft Rejection / immunology
  • Graft Rejection / prevention & control*
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / etiology
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / pharmacokinetics*
  • Kidney Transplantation* / adverse effects
  • Kidney Transplantation* / immunology
  • Male
  • Pharmacogenetics
  • Tacrolimus / adverse effects
  • Tacrolimus / pharmacokinetics*
  • Treatment Outcome

Substances

  • ABCB1 protein, human
  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Antihypertensive Agents
  • Immunosuppressive Agents
  • Amlodipine
  • CYP3A5 protein, human
  • Cytochrome P-450 CYP3A
  • CYP3A4 protein, human
  • Tacrolimus