Atypical severe central serous chorioretinopathy in a patient with systemic lupus erythematosus improved with a rapid reduction in glucocorticoid

Mod Rheumatol. 2013 Jan;23(1):172-4. doi: 10.1007/s10165-012-0629-6. Epub 2012 Mar 25.

Abstract

A 36-year-old woman was diagnosed with systemic lupus erythematosus (SLE). Seven days after beginning glucocorticoid treatment, she developed reduced visual acuity, and atypical severe central serous chorioretinopathy (CSC) was confirmed. Since glucocorticoid use is an important risk factor for CSC, the PSL was reduced, tacrolimus was added, and the visual acuity improved rapidly. Reduction in glucocorticoid combined with the use of immunosuppressive agents is one option for preventing a deterioration in atypical severe CSC while still controlling SLE.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Central Serous Chorioretinopathy / chemically induced*
  • Central Serous Chorioretinopathy / complications
  • Central Serous Chorioretinopathy / physiopathology
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / adverse effects*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / drug therapy*
  • Lupus Erythematosus, Systemic / physiopathology
  • Methylprednisolone / therapeutic use
  • Prednisolone / therapeutic use
  • Recovery of Function
  • Tacrolimus / therapeutic use
  • Treatment Outcome
  • Vision Disorders / chemically induced*
  • Vision Disorders / complications
  • Vision Disorders / physiopathology
  • Visual Acuity / physiology*

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Prednisolone
  • Tacrolimus
  • Methylprednisolone