Oligo Tröger's bases--new molecular scaffolds

Chem Soc Rev. 2012 May 21;41(10):3839-58. doi: 10.1039/c2cs15307f. Epub 2012 Mar 22.

Abstract

Oligo Tröger's bases are compounds containing two or more Tröger's base subunits (1,5-methanodiareno[b,f][1,5]diazocines) sharing one or more arene parts. Due to their interesting molecular shapes, these compounds are studied as chiral molecular tweezers, clips, cavitands, clefts, calixes, etc. This review includes all available data on oligo Tröger's bases, and introduces their preparation and properties to a wide audience.