Inhalation study of polymethyl methacrylate following radiologist exposure during percutaneous vertebroplasty

Skeletal Radiol. 2013 Feb;42(2):203-7. doi: 10.1007/s00256-012-1370-0. Epub 2012 Mar 23.

Abstract

Objective: To assess the atmospheric concentrations of methyl methacrylate (MMA) vapors during percutaneous vertebroplasty for the interventional radiologist and the other operating room staff.

Materials and methods: During percutaneous vertebroplasty, a polymethyl methacrylate (PMMA) mixture (about 20 mL) was prepared with a mixing system in a normally ventilated room. Atmospheric concentrations of MMA vapors were measured by a gas absorbent badge for individual exposure (GABIE) passive sampler attached to the surgical gowns of the interventional radiologist and the other operating room staff over a period of 460 min. Active sampling was performed over 15 min with an individual pump placed near the breathing zone of the radiologist. MMA vapor concentrations were then measured using gas chromatography and activated charcoal tubes.

Results: Mean MMA vapor concentrations measured by the GABIEs over the period of 460 min were 0.51 parts per million (ppm) for the radiologist and 0.22 ppm for the other operating room staff. The emission peaks measured by using charcoal tubes over 15 min were 3.7 ppm.

Conclusion: MMA vapor concentrations during percutaneous vertebroplasty were well below the recommended maximum exposure of 100 ppm over the course of an 8-h workday.

MeSH terms

  • Administration, Inhalation
  • Air Pollutants, Occupational / analysis*
  • Bone Cements / analysis*
  • France
  • Humans
  • Occupational Exposure / analysis*
  • Operating Rooms*
  • Physicians
  • Polymethyl Methacrylate / analysis*
  • Radiography, Interventional*
  • Vertebroplasty*

Substances

  • Air Pollutants, Occupational
  • Bone Cements
  • Polymethyl Methacrylate