Acceptability of misoprostol-only medical termination of pregnancy compared with vacuum aspiration: an international, multicentre trial

BJOG. 2012 Jun;119(7):817-23. doi: 10.1111/j.1471-0528.2012.03310.x. Epub 2012 Mar 20.

Abstract

Objective: To compare women's acceptance of misoprostol-only medical termination of pregnancy (TOP) with surgical TOP.

Design: Prospective cohort study.

Setting: Termination of pregnancy clinics in New Delhi, Mumbai, Hanoi, Tbilisi, Trivandrum and Yerevan.

Population: Women requesting TOP, at 63 days of gestation or less, at study sites where both medical and surgical methods were available.

Methods: Serial surveys eliciting measures of women's satisfaction and acceptance of TOP method were administered. Data were analysed using cross-tabulation and logistic regression to determine if TOP method was predictive of acceptability.

Main outcome measures: Patient acceptance.

Results: High acceptability of both surgical and misoprostol-only TOP.

Conclusions: Where medical TOP with mifepristone is not available, misoprostol-only medical TOP is acceptable to women who have the choice between medical or surgical techniques.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortifacient Agents, Nonsteroidal* / administration & dosage
  • Abortion, Induced / methods*
  • Adult
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Logistic Models
  • Misoprostol* / administration & dosage
  • Patient Preference / statistics & numerical data
  • Patient Satisfaction / statistics & numerical data*
  • Pregnancy
  • Prospective Studies
  • Vacuum Curettage*

Substances

  • Abortifacient Agents, Nonsteroidal
  • Misoprostol

Associated data

  • ISRCTN/ISRCTN10531821