Androgen receptors, sex behavior, and aggression

Neuroendocrinology. 2012;96(2):131-40. doi: 10.1159/000337663. Epub 2012 Sep 14.

Abstract

Androgens are intricately involved in reproductive and aggressive behaviors, but the role of the androgen receptor in mediating these behaviors is less defined. Further, activity of the hypothalamic-pituitary-gonadal axis and hypothalamic-pituitary-adrenal axis can influence each other at the level of the androgen receptor. Knowledge of the mechanisms for androgens' effects on behaviors through the androgen receptor will guide future studies in elucidating male reproductive and aggressive behavior repertoires.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aggression / drug effects
  • Aggression / physiology*
  • Animals
  • Estrogens / metabolism
  • Estrogens / pharmacology
  • Female
  • Humans
  • Male
  • Receptors, Androgen / metabolism*
  • Sexual Behavior / drug effects
  • Sexual Behavior / physiology*

Substances

  • Estrogens
  • Receptors, Androgen