The U(VI) atom in the title complex, [U(C(17)H(15)N(3)O(2)S)O(2)(C(2)H(6)OS)], exists within a distorted penta-gonal-pyramidal geometry where the oxide atoms occupy axial positions [O-U-O = 177.84 (14)°] and the penta-gonal plane is defined by the N(2)O(2) atoms of the tetra-dentate Schiff base ligand and the O atom of the dimethyl sulfoxide mol-ecule. In the crystal, centrosymmetric aggregates are formed via pairs of C-H⋯O inter-actions. The azomethine C=N atoms and ethyl-thiolyl group are disordered over two orientations in a 0.828 (3):0.172 (3) ratio.