Urinary bladder cancer: role of MR imaging

Radiographics. 2012 Mar-Apr;32(2):371-87. doi: 10.1148/rg.322115125.

Abstract

Urinary bladder cancer is a heterogeneous disease with a variety of pathologic features, cytogenetic characteristics, and natural histories. It is the fourth most common cancer in males and the tenth most common cancer in females. Urinary bladder cancer has a high recurrence rate, necessitating long-term surveillance after initial therapy. Early detection is important, since up to 47% of bladder cancer-related deaths may have been avoided. Conventional computed tomography (CT) and magnetic resonance (MR) imaging are only moderately accurate in the diagnosis and local staging of bladder cancer, with cystoscopy and pathologic staging remaining the standards of reference. However, the role of newer MR imaging sequences (eg, diffusion-weighted imaging) in the diagnosis and local staging of bladder cancer is still evolving. Substantial advances in MR imaging technology have made multiparametric MR imaging a feasible and reasonably accurate technique for the local staging of bladder cancer to optimize treatment. In addition, whole-body CT is the primary imaging technique for the detection of metastases in bladder cancer patients, especially those with disease that invades muscle.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery
  • Carcinoma, Transitional Cell / diagnosis*
  • Carcinoma, Transitional Cell / diagnostic imaging
  • Carcinoma, Transitional Cell / epidemiology
  • Carcinoma, Transitional Cell / genetics
  • Carcinoma, Transitional Cell / pathology
  • Carcinoma, Transitional Cell / surgery
  • Cystoscopy
  • Early Detection of Cancer
  • Female
  • Fibroblast Growth Factors / genetics
  • Genes, ras
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Muscle, Smooth / pathology
  • Neoplasm Invasiveness
  • Neoplasm Staging / methods
  • Positron-Emission Tomography
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / diagnostic imaging
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / genetics
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery
  • Urography / methods

Substances

  • Fibroblast Growth Factors