We have determined the complete mitochondrial genome (NC_016427) of the Korean red-backed vole, Myodes regulus, which is distributed in South Korea. The total length of the M. regulus mitogenome is 16,379 bp, with a base composition of 33.0% A, 26.7% T, 27.1% C, and 13.2% G. The total length of the 13 protein-coding genes is 11,396 bp long.