Abstract
The purpose of this case report is to demonstrate the effectiveness of a matrix consisting of recombinant human platelet-derived growth factor BB (rhPDGF-BB)-hydrated cancellous allogenic block graft in the reconstruction of large local human alveolar ridge defects. The results suggest improved bone regeneration when combining rhPDGF-BB with the allogenic block graft. The clinical and histologic evidence of new bone formation as well as bone remodeling supports the clinical potency of this growth factor-mediated therapy.
MeSH terms
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Alveolar Ridge Augmentation / methods*
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Angiogenesis Inducing Agents / therapeutic use*
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Becaplermin
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Biopsy
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Bone Density / physiology
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Bone Regeneration / physiology
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Bone Remodeling / physiology
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Bone Transplantation / methods*
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Bone Transplantation / pathology
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Follow-Up Studies
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Humans
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Maxilla / pathology
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Maxilla / surgery
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Osteogenesis / physiology
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Piezosurgery
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Plastic Surgery Procedures / methods*
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Proto-Oncogene Proteins c-sis / therapeutic use*
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Recombinant Proteins
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Tomography, X-Ray Computed
Substances
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Angiogenesis Inducing Agents
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Proto-Oncogene Proteins c-sis
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Recombinant Proteins
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Becaplermin