Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4

Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4058-61. doi: 10.1002/anie.201107011. Epub 2012 Mar 12.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Conotoxins / chemistry
  • Conotoxins / pharmacology*
  • Humans
  • Isomerism
  • Molecular Structure
  • NAV1.4 Voltage-Gated Sodium Channel
  • Sodium Channel Blockers
  • Sodium Channels / drug effects*

Substances

  • Conotoxins
  • NAV1.4 Voltage-Gated Sodium Channel
  • SCN4A protein, human
  • Sodium Channel Blockers
  • Sodium Channels
  • mu-conotoxin PIIIA