Antioxidative flavonol glycosides from the flowers of Abelmouschus manihot

J Nat Med. 2013 Jan;67(1):78-85. doi: 10.1007/s11418-012-0651-1. Epub 2012 Mar 10.

Abstract

Bioassay-guided fractionation led to the isolation of six new flavonol glycosides, floramanosides A (1), B (2), C (3), D (4), E (5), and F (6), from the flowers of Abelmouschus manihot. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D- and 2D-NMR). Activity screening results showed that the compounds had 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Reductase / metabolism
  • Antioxidants / chemistry*
  • Biphenyl Compounds / chemistry
  • Flavonols / chemistry*
  • Flowers / chemistry*
  • Glycosides / chemistry*
  • Magnetic Resonance Spectroscopy
  • Manihot / chemistry*
  • Mass Spectrometry
  • Molecular Structure
  • Picrates / chemistry

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Flavonols
  • Glycosides
  • Picrates
  • 1,1-diphenyl-2-picrylhydrazyl
  • Aldehyde Reductase