Acquisition of hydrogenosomal presequences: examples from Trichomonas vaginalis

Dongliang Yu; Yue Wang; Xu Fang; Songnian Hu; Petrus Tang; Yan Fu

doi:10.1111/j.1574-6968.2012.02541.x

Acquisition of hydrogenosomal presequences: examples from Trichomonas vaginalis

FEMS Microbiol Lett. 2012 May;330(2):127-31. doi: 10.1111/j.1574-6968.2012.02541.x. Epub 2012 Apr 2.

Authors

Dongliang Yu¹, Yue Wang, Xu Fang, Songnian Hu, Petrus Tang, Yan Fu

Affiliation

¹ Center of Biomedical and Health, Hangzhou Normal University, Hangzhou, China.

PMID: 22404599
DOI: 10.1111/j.1574-6968.2012.02541.x

Abstract

Presequences play an important role in protein import into mitochondria-like organelles. Acquisition pathways have been revealed for some mitochondrial presequences, but little is known about hydrogenosomal presequences. Here we investigated the hydrogenosomal proteins of Trichomonas vaginalis and suggest that several hydrogenosomal presequences probably evolved from pre-existing sequences that were thereafter modified.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Molecular Sequence Data
Organelles / enzymology
Protein Sorting Signals*
Protein Transport
Protozoan Proteins / genetics*
Protozoan Proteins / metabolism*
Sequence Alignment
Trichomonas vaginalis / enzymology*
Trichomonas vaginalis / genetics*

Substances

Protein Sorting Signals
Protozoan Proteins