Wavy and elevated retinal pigment epithelial line in optical coherence tomographic images of eyes with atypical Vogt-Koyanagi-Harada disease

Graefes Arch Clin Exp Ophthalmol. 2012 Sep;250(9):1399-402. doi: 10.1007/s00417-012-1977-9. Epub 2012 Mar 7.

Abstract

Purpose: We report the changes of the retinal pigment epithelium (RPE) determined by optical coherence tomography in a patient with atypical Vogt-Koyanagi-Harada (VKH) disease during the recovery phase.

Method: Case presentation.

Results: A 74-year-old woman presented with a central scotoma associated with disc hyperemia, serous retinal detachment, and scleral thickening in her left eye, and was diagnosed with VKH. OCT showed a serous retinal detachment and a wavy RPE contour that corresponded to the choroidal folds. The OCT images clearly showed the dynamic changes of the retina, RPE, and choroid during the recovery phase.

Conclusions: The OCT was found to be more sensitive in detecting the choroidal folds than angiography. OCT images are valuable not only in the diagnosis, but also for monitoring the morphology of the retina and choroid during the course of VKH.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Betamethasone / therapeutic use
  • Choroid Diseases / diagnosis
  • Female
  • Fluorescein Angiography
  • Glucocorticoids / therapeutic use
  • Humans
  • Hyperemia / diagnosis
  • Indocyanine Green
  • Microscopy, Acoustic
  • Optic Nerve Diseases / diagnosis
  • Retinal Detachment / diagnosis
  • Retinal Pigment Epithelium / pathology*
  • Scotoma / diagnosis
  • Tomography, Optical Coherence*
  • Tomography, X-Ray Computed
  • Uveomeningoencephalitic Syndrome / diagnosis*
  • Uveomeningoencephalitic Syndrome / drug therapy

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Glucocorticoids
  • Betamethasone
  • Indocyanine Green