Abstract
In this work, we developed a portable integrated microchip of loop-mediated isothermal nucleic acid amplification (LAMP). This chip, with sample-to-answer capability, could perform rapid DNA release, exponential signal amplification and naked-eye result read-out in single or multiplex format. We call it iμLAMP, namely integrated micro-LAMP, which was successfully used for point-of-care identification of bacteria.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacteria / genetics*
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Bacteria / isolation & purification*
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Bacterial Infections / diagnosis
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Base Sequence
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DNA, Bacterial / genetics*
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DNA, Bacterial / isolation & purification
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Equipment Design
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Humans
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Microfluidic Analytical Techniques*
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Molecular Sequence Data
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Mycobacterium tuberculosis / genetics
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Mycobacterium tuberculosis / isolation & purification
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Nucleic Acid Amplification Techniques / instrumentation*
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Point-of-Care Systems*