In-hospital monitoring of T-wave alternans in a case of amiodarone-induced torsade de pointes: clinical and methodologic insights

Tomonori Kawaguchi; Nobuhiro Takasugi; Tomoki Kubota; Mieko Takasugi; Hiromitsu Kanamori; Hiroaki Ushikoshi; Arihiro Hattori; Takuma Aoyama; Masanori Kawasaki; Kazuhiko Nishigaki; Genzou Takemura; Shinya Minatoguchi; Richard L Verrier

doi:10.1093/europace/eus040

In-hospital monitoring of T-wave alternans in a case of amiodarone-induced torsade de pointes: clinical and methodologic insights

Europace. 2012 Sep;14(9):1372-4. doi: 10.1093/europace/eus040. Epub 2012 Mar 1.

Authors

Tomonori Kawaguchi¹, Nobuhiro Takasugi, Tomoki Kubota, Mieko Takasugi, Hiromitsu Kanamori, Hiroaki Ushikoshi, Arihiro Hattori, Takuma Aoyama, Masanori Kawasaki, Kazuhiko Nishigaki, Genzou Takemura, Shinya Minatoguchi, Richard L Verrier

Affiliation

¹ Division of Cardiovascular Medicine, Department of Internal Medicine, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.

PMID: 22389418
DOI: 10.1093/europace/eus040

Abstract

We report a case of macroscopic T-wave alternans occurring 30 min before the onset of amiodarone-induced torsade de pointes, illustrating a means to monitor for proarrhythmia.

Publication types

Case Reports

MeSH terms

Aged
Amiodarone / adverse effects*
Anti-Arrhythmia Agents / adverse effects*
Atrial Fibrillation / diagnosis
Atrial Fibrillation / diagnostic imaging
Atrial Fibrillation / drug therapy
Bundle-Branch Block / diagnosis
Carbazoles / therapeutic use
Carvedilol
Electrocardiography / methods
Heart Failure / drug therapy
Humans
Hypertension, Pulmonary / drug therapy
Magnesium / therapeutic use
Male
Propanolamines / therapeutic use
Torsades de Pointes / chemically induced*
Torsades de Pointes / diagnostic imaging
Treatment Outcome
Ultrasonography

Substances

Anti-Arrhythmia Agents
Carbazoles
Propanolamines
Carvedilol
Magnesium
Amiodarone