Engineered 3D microporous gelatin scaffolds to study cell migration

Chem Commun (Camb). 2012 Apr 11;48(29):3512-4. doi: 10.1039/c2cc17006j. Epub 2012 Feb 29.

Abstract

Here we present a facile method to fabricate microporous hydrogel scaffolds that can be functionalized with a chemokine gradient. These scaffolds allow studying cellular responses in a 3D environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Becaplermin
  • Cell Movement*
  • Fibroblasts / physiology*
  • Gelatin / chemistry
  • Hydrogels / chemistry
  • Porosity
  • Proto-Oncogene Proteins c-sis / chemistry
  • Proto-Oncogene Proteins c-sis / physiology
  • Skin / cytology
  • Tissue Scaffolds*

Substances

  • Hydrogels
  • Proto-Oncogene Proteins c-sis
  • Becaplermin
  • Gelatin