Abstract
We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug-resistance determinants.
MeSH terms
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Aged
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Bacterial Proteins / genetics
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Canada / epidemiology
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Disease Outbreaks*
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Escherichia coli Infections / diagnosis
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Escherichia coli Infections / epidemiology*
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Escherichia coli Infections / microbiology
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Genome, Bacterial
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Humans
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Infant
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Male
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Sequence Analysis, DNA
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Shiga-Toxigenic Escherichia coli / genetics
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Shiga-Toxigenic Escherichia coli / isolation & purification*
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Travel*