A non-metal catalysed oxidation of primary azides to nitriles at ambient temperature

Manjunath Lamani; Pradeep Devadig; Kandikere Ramaiah Prabhu

doi:10.1039/c2ob06949k

A non-metal catalysed oxidation of primary azides to nitriles at ambient temperature

Org Biomol Chem. 2012 Apr 14;10(14):2753-9. doi: 10.1039/c2ob06949k. Epub 2012 Feb 27.

Authors

Manjunath Lamani¹, Pradeep Devadig, Kandikere Ramaiah Prabhu

Affiliation

¹ Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India.

PMID: 22371205
DOI: 10.1039/c2ob06949k

Abstract

A novel non-metal catalyzed oxidation of organic azides to nitriles under solvent-free conditions is presented employing catalytic amounts of KI, and DABCO in aq. TBHP at room temperature. This non-metal catalyzed oxidation of azides provides good selectivity as double and triple bonds were not oxidized under the present reaction conditions.