[Osteoimmunology - IMMUNOBONE - Understanding the interaction between bone and immune system]

Z Rheumatol. 2012 Feb;71(2):138-9. doi: 10.1007/s00393-012-0954-3.
[Article in German]

Abstract

The special program "Osteoimmunology" under the leadership of the Universities of Erlangen, Jena, Gießen and Münster, is investigating in 27 projects clarification approaches on the causes of inflammatory rheumatic diseases, such as rheumatoid arthritis and ankylosing spondylitis with the aim of developing new forms of treatment. The molecular mechanisms involved in bone damage and the interaction between the immune system and bone and cartilage are topics of research.

Publication types

  • Review

MeSH terms

  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / genetics
  • Arthritis, Rheumatoid / immunology*
  • Bone and Bones / immunology*
  • Cartilage / immunology
  • Humans
  • Immunogenetic Phenomena / genetics
  • Immunogenetic Phenomena / immunology
  • Spondylitis, Ankylosing / drug therapy
  • Spondylitis, Ankylosing / genetics
  • Spondylitis, Ankylosing / immunology*
  • Translational Research, Biomedical
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • Tumor Necrosis Factor-alpha / blood

Substances

  • Antirheumatic Agents
  • Tumor Necrosis Factor-alpha