[Clinico-epidemiological characteristics of HIV-positive immigrants: study of 371 cases]

Enferm Infecc Microbiol Clin. 2012 Oct;30(8):441-51. doi: 10.1016/j.eimc.2012.01.009. Epub 2012 Feb 23.
[Article in Spanish]

Abstract

Introduction: The number of HIV-positive immigrants have increased in Spain in the last few years, and now represent a significant proportion of the epidemic. Our objective is to describe the clinico-epidemiological characteristics of HIV-positive immigrants seen in a specialist unit in Madrid.

Material and methods: Retrospective study. Every patient born in a country other than Spain and attended an HIV Unit in Madrid between 1992 and 2009 was included.

Results: Of the 371 patients included, 53.1% were Latin Americans, 24.5% Sub-Saharan Africans, and 22.4% others), and 60% were males. Immigrants represented 0.3% of new patients in 1992 and rose to 49.2% in 2009. The principal reason for HIV testing had been pregnancy/delivery among women (32.7%) and having a category-B disease among men (17.4%). Sexual transmission accounted for 92% of patients. Tuberculosis was the principal AIDS-diagnosing illness. Respectively 90%, 7.7%, 60%, 26.7%, 96% and 95% of patients had an IgG for HAV, HCV, Toxoplasma, Treponema, CMV and VZV. VHB-Ags+: 5.4%; PPD+: 17%. At least one syphilis episode was recorded in 62% of the men who have sex with men (MSM). Prevalence of HLA-B5701 was 6%, 0.9% and 3.8% in Caucasians, Amerindians and Afro-Americans, respectively.

Conclusions: Immigrants represent a significant proportion of new HIV-positive patients. It is a very heterogeneous group according to their clinical and epidemiological characteristics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology
  • AIDS-Related Opportunistic Infections / ethnology
  • Adult
  • Africa South of the Sahara / ethnology
  • Asia / ethnology
  • Comorbidity
  • Cross-Sectional Studies
  • Emigrants and Immigrants / statistics & numerical data*
  • Europe / ethnology
  • Female
  • HIV Infections / epidemiology
  • HIV Infections / ethnology*
  • HIV Infections / transmission
  • HIV Seroprevalence / trends
  • HIV-1
  • HIV-2
  • HLA-B Antigens / genetics
  • Hospitals, University / statistics & numerical data
  • Hospitals, Urban / statistics & numerical data
  • Humans
  • Latin America / ethnology
  • Lymphocyte Count
  • Male
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / ethnology
  • Racial Groups / genetics
  • Retrospective Studies
  • Risk Factors
  • Sexuality / statistics & numerical data
  • Socioeconomic Factors
  • Spain / epidemiology
  • Tuberculosis / epidemiology
  • Tuberculosis / ethnology

Substances

  • HLA-B Antigens
  • HLA-B*57:01 antigen