Abstract
Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency disease with unique and characteristic features. In 1994, the responsible gene for WAS, the WASP gene on X-chromosome, was identified. Since then, renewed clinical and basic researches of WAS have started and remarkably developed. I will comment on recent progress in the clinical and basic researches of WAS, including some topics reported by our and other groups.
MeSH terms
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Animals
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Eczema / immunology
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Genes, X-Linked / genetics
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Genes, X-Linked / immunology
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Genetic Therapy
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Hematopoietic Stem Cell Transplantation
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Hemorrhage / immunology
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Humans
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Immunity / genetics
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Infant, Newborn
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Male
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Mutation / genetics
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Thrombocytopenia / immunology
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Wiskott-Aldrich Syndrome / diagnosis*
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Wiskott-Aldrich Syndrome / genetics*
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Wiskott-Aldrich Syndrome / immunology
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Wiskott-Aldrich Syndrome Protein / genetics
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Wiskott-Aldrich Syndrome Protein / metabolism*
Substances
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Wiskott-Aldrich Syndrome Protein