CREMα overexpression decreases IL-2 production, induces a T(H)17 phenotype and accelerates autoimmunity

J Mol Cell Biol. 2012 Apr;4(2):121-3. doi: 10.1093/jmcb/mjs004. Epub 2012 Feb 20.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoimmunity*
  • Cyclic AMP Response Element Modulator / genetics
  • Cyclic AMP Response Element Modulator / metabolism*
  • Down-Regulation*
  • Gene Expression
  • Humans
  • Interleukin-17 / genetics
  • Interleukin-17 / immunology
  • Interleukin-2 / genetics
  • Interleukin-2 / immunology*
  • Mice
  • Mice, Knockout
  • Th17 Cells / immunology*

Substances

  • Interleukin-17
  • Interleukin-2
  • Cyclic AMP Response Element Modulator