NO serves as a signaling intermediate downstream of H₂O₂ to modulate dynamic microtubule cytoskeleton during responses to VD-toxins in Arabidopsis

Plant Signal Behav. 2012 Feb;7(2):174-7. doi: 10.4161/psb.18768. Epub 2012 Feb 1.

Abstract

Although hydrogen peroxide (H₂O₂) and nitric oxide (NO) can act as an upstream signaling molecule to modulate the dynamic microtubule cytoskeleton during the defense responses to Verticillium dahliae (VD) toxins in Arabidopsis, it is not known the relationship between these two signaling molecules. Here, we show that VD-toxin-induced NO accumulation was dependent on prior H₂O₂ production, NO is downstream of H₂O₂ in the signaling process, and that H₂O₂ acted synergistically with NO to modulate the dynamic microtubule cytoskeleton responses to VD-toxins in Arabidopsis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / drug effects*
  • Arabidopsis / metabolism
  • Arabidopsis / microbiology
  • Cytoskeleton / drug effects*
  • Cytoskeleton / metabolism
  • Hydrogen Peroxide / metabolism*
  • Microtubules / drug effects
  • Microtubules / metabolism
  • Mycotoxins / pharmacology*
  • Nitric Oxide / metabolism*
  • Plant Diseases / microbiology
  • Plant Immunity / physiology*
  • Signal Transduction
  • Verticillium / metabolism*

Substances

  • Mycotoxins
  • Nitric Oxide
  • Hydrogen Peroxide