Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus

J Biomol NMR. 2012 Apr;52(4):365-70. doi: 10.1007/s10858-012-9612-y. Epub 2012 Feb 14.

Authors

Piotr Borowicz¹, Elżbieta Bednarek, Wojciech Bocian, Jerzy Sitkowski, Beata Jaworska, Jerzy Mikołajczyk, Tadeusz Głąbski, Dorota Stadnik, Weronika Surmacz, Monika Bogiel, Lech Kozerski

Affiliation

¹ Institute of Biotechnology and Antibiotics, 02-516 Warsaw, Poland.

PMID: 22350952
DOI: 10.1007/s10858-012-9612-y

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Insulin / chemistry*
Insulin / genetics
Models, Molecular
Mutant Proteins / chemistry
Nuclear Magnetic Resonance, Biomolecular
Protein Conformation
Recombinant Proteins / chemistry

Substances

Insulin
Mutant Proteins
Recombinant Proteins