In the title compound, C(15)H(15)ClN(2)O(2)S, the 2-amino-acetamide N-C(=O)-C-N unit is approximately planar, with an r.m.s. deviation of 0.020 (4) Å. The central thio-phene ring makes dihedral angles of 7.84 (11) and 88.11 (11)°, respectively, with the 2-amino-acetamide unit and the 2-chloro-phenyl ring. An intra-molecular N-H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, mol-ecules are linked by an N-H⋯O hydrogen bond and weak C-H⋯O inter-actions into a chain along the c axis. A C-H⋯π inter-action is also present.