Comparison of the clinicopathological characteristics of young and elderly patients with gastric carcinoma: a meta analysis

J Surg Oncol. 2012 Sep 1;106(3):346-52. doi: 10.1002/jso.23004. Epub 2012 Feb 13.

Abstract

To evaluate the relationship between age and clinicopathological characteristics in gastric carcinoma patients, we performed the meta-analysis based on nine retrospective clinical trials. Comparing elderly patients with young patients it showed lower male/female ratio, more diffuse GC, more Borrmann type IV, more poorly differentiated carcinoma, more peritoneal metastasis, less vascular invasion, fewer partial resections, and better 5-year survival rate. These particular age-related characteristics need to be further investigated.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Aged
  • Carcinoma / mortality*
  • Carcinoma / pathology*
  • Carcinoma / surgery
  • Humans
  • Neoplasm Invasiveness
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Stomach / pathology
  • Stomach Neoplasms / mortality*
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery
  • Survival Rate