Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

Kiyoshi Sasaki; Susanne Bohnenberger; Kumiko Hayashi; Thorsten Kunkelmann; Dai Muramatsu; Albrecht Poth; Ayako Sakai; Susan Salovaara; Noriho Tanaka; B Claire Thomas; Makoto Umeda

doi:10.1016/j.mrgentox.2012.01.009

Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

Mutat Res. 2012 Apr 11;744(1):42-53. doi: 10.1016/j.mrgentox.2012.01.009. Epub 2012 Feb 4.

Authors

Kiyoshi Sasaki¹, Susanne Bohnenberger, Kumiko Hayashi, Thorsten Kunkelmann, Dai Muramatsu, Albrecht Poth, Ayako Sakai, Susan Salovaara, Noriho Tanaka, B Claire Thomas, Makoto Umeda

Affiliation

¹ Hatano Research Institute, Food and Drug Safety Center, Hadano, Kanagawa, Japan. sasaki.k@fdsc.or.jp

PMID: 22331008
DOI: 10.1016/j.mrgentox.2012.01.009

Abstract

This catalogue is a display of focus photos representative of the BALB/c 3T3 cell transformation assay (CTA). It is intended as a visual aid for the identification and the scoring of foci in the conduct of the assay. A proper training from experienced personnel together with the protocol reported in this issue and the present photo catalogue will support method transfer and consistency in the assay results.

MeSH terms

Animal Testing Alternatives / methods
Animals
Audiovisual Aids*
BALB 3T3 Cells*
Carcinogenicity Tests / methods*
Carcinogens / toxicity
Catalogs as Topic*
Cell Transformation, Neoplastic*
Dose-Response Relationship, Drug
Mice
Photography*

Substances

Carcinogens