Development of an electrochemical cholesterol sensor system for food analysis

Anal Sci. 2012;28(2):187-91. doi: 10.2116/analsci.28.187.

Abstract

In this article, we report on a food-cholesterol monitoring sensor based on a non-enzymatic approach. Amorphous and single-crystal gold electrodes were modified with an alkanethiol self-assembled monolayer to quantify it by voltammetry. We first discuss the basic characteristics of these sensors and provide more information about the instrument developed by JSK Co. This instrument is a battery-operated handheld voltammetric analyzer, which mounts a sensor chip to monitor cholesterol contents in food samples. The sensor showed excellent linearity with the cholesterol concentration; egg-yolk samples were analyzed to give an excellent agreement between the values obtained by the sensor (1.4 mM) and chromatography (1.1 mM).

MeSH terms

  • Chemistry Techniques, Analytical / instrumentation*
  • Cholesterol / analysis*
  • Cholesterol / chemistry
  • Electrochemistry / instrumentation
  • Electrochemistry / methods*
  • Electrodes
  • Food Analysis / instrumentation
  • Food Analysis / methods*
  • Sulfhydryl Compounds / chemistry

Substances

  • Sulfhydryl Compounds
  • Cholesterol