Prevalence of antibiotic resistance among Acinetobacter baumannii isolates from Aleppo, Syria

Am J Infect Control. 2012 Oct;40(8):776-7. doi: 10.1016/j.ajic.2011.09.019. Epub 2012 Feb 2.

Abstract

This study describes and analyzes Acinetobacter baumannii antibiotic susceptibly profile in Aleppo, Syria, thus providing vital information for guiding treatment of A baumannii infections. Two hundred sixty nonrepetitive A baumannii isolates were studied over 3.5 years. Resistance rates are at the higher end of globally reported levels. Newer cephalosporins and β-lactamase-resistant agents are becoming practically ineffective. Better activity is limited to carbapenems and colistin, which elicited the highest susceptibility levels.

MeSH terms

  • Acinetobacter Infections / drug therapy
  • Acinetobacter Infections / epidemiology
  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / drug effects*
  • Acinetobacter baumannii / isolation & purification
  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Carbapenems / pharmacology
  • Carbapenems / therapeutic use
  • Child
  • Child, Preschool
  • Colistin / pharmacology
  • Colistin / therapeutic use
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Prevalence
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / microbiology*
  • Retrospective Studies
  • Syria / epidemiology
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / microbiology*
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Carbapenems
  • Colistin