Three new steroidal glycosides from roots of Reineckia carnea

Nat Prod Res. 2013;27(2):85-92. doi: 10.1080/14786419.2012.658797. Epub 2012 Feb 3.

Abstract

Two new spirostanols and a new furostanol, reinocarnoside A (1), B (2) and C (3), were isolated from the roots of Reineckia carnea, together with two known compounds, (25S)-1β,3β,4β-trihydroxyspirostan-5β-yl-O-β-D-glucopyranoside (4), kitigenin-5β-O-β-D-glucopyranoside (5). The structures of three new compounds were elucidated by spectroscopic methods including 1-D NMR, 2-D NMR and MS spectrums, and their anticancer activities were evaluated by MTT method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Glycosides / analysis*
  • Glycosides / isolation & purification
  • Glycosides / pharmacology
  • Hep G2 Cells / drug effects
  • Humans
  • Liliaceae / chemistry*
  • MCF-7 Cells / drug effects
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure
  • Plant Extracts / analysis*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Roots / chemistry*
  • Spirostans / analysis*
  • Spirostans / isolation & purification
  • Spirostans / pharmacology
  • Sterols / analysis*
  • Sterols / isolation & purification
  • Sterols / pharmacology
  • Tetrazolium Salts
  • Thiazoles

Substances

  • Antineoplastic Agents
  • Glycosides
  • Plant Extracts
  • Spirostans
  • Sterols
  • Tetrazolium Salts
  • Thiazoles
  • furostanol glycoside
  • thiazolyl blue