Abstract
A selective and sensitive turn-on fluorescent NIR probe for cysteine has been developed. Cleavage of 2,4-dinitrobenzenesulfonyl (DNBS) with thiols switches the weakly fluorescent aza-BODIPY dye (λ(em) = 734 nm, Φ(f) = 0.03) to a strongly fluorescent species in the NIR region (λ(em) = 755 nm, Φ(f) = 0.14).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzenesulfonates / chemistry
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Boron Compounds / chemistry*
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Cysteine / analysis*
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Fluorescent Dyes / chemistry*
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Spectrometry, Fluorescence
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Sulfhydryl Compounds / chemistry
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Benzenesulfonates
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Boron Compounds
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Fluorescent Dyes
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Sulfhydryl Compounds
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dinitrobenzenesulfonic acid
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Cysteine