Epidemiology of amyotrophic lateral sclerosis patients in a centre in Buenos Aires

Arq Neuropsiquiatr. 2011 Dec;69(6):867-70. doi: 10.1590/s0004-282x2011000700003.

Abstract

Sporadic amyotrophic lateral sclerosis (sALS) is considered a multifactorial disease with genetic and environmental factors causing motor neuron degeneration.

Objective: To describe the epidemiological and occupational characteristics of patients with sALS who attended the Ramos Mejía Hospital at Buenos Aires, Argentina.

Method: We analyzed the medical records of sALS patients diagnosed between 2001 and 2008. All occupations were coded according to the International Standard Classification of Occupation (ISCO).

Results: 187 patients were assessed, 38.5% were women and 61.5% men. Mean age at diagnosis was 55 years. 16% of them came from rural areas; 68% of the studied population had no health insurance. 40% were employed in elementary occupations, 19 were technicians and 8 handicraftsmen.

Conclusion: The most represented profession was elementary occupation. A large proportion of patients came from rural areas, which might suggest an increased risk of environmental exposure to an unknown agent in those regions.

MeSH terms

  • Adult
  • Aged
  • Amyotrophic Lateral Sclerosis / epidemiology*
  • Amyotrophic Lateral Sclerosis / etiology
  • Argentina / epidemiology
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Occupations
  • Risk Factors
  • Rural Population / statistics & numerical data
  • Young Adult