Rupestines F-M, new guaipyridine sesquiterpene alkaloids from Artemisia rupestris

Fei He; Alfarius Eko Nugroho; Chin Piow Wong; Yusuke Hirasawa; Osamu Shirota; Hiroshi Morita; Haji Akber Aisa

doi:10.1248/cpb.60.213

Rupestines F-M, new guaipyridine sesquiterpene alkaloids from Artemisia rupestris

Chem Pharm Bull (Tokyo). 2012;60(2):213-8. doi: 10.1248/cpb.60.213.

Authors

Fei He¹, Alfarius Eko Nugroho, Chin Piow Wong, Yusuke Hirasawa, Osamu Shirota, Hiroshi Morita, Haji Akber Aisa

Affiliation

¹ Faculty of Pharmaceutical Sciences, Hoshi University, 2–4–41 Ebara, Shinagawa-ku, Tokyo, Japan.

PMID: 22293480
DOI: 10.1248/cpb.60.213

Abstract

Eight new guaipyridine sesquiterpene alkaloids, rupestines F-M (1-8) were isolated from the leaves of Artemisia rupestris and their structures were elucidated on the basis of 2D-NMR data. The absolute configurations of 1-8 have been assigned by comparison of their experimental and calculated circular dichroism (CD) spectra.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids / chemistry*
Artemisia / chemistry*
Circular Dichroism
Computer Simulation
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Leaves / chemistry*
Pyrimidines / chemistry*
Sesquiterpenes / chemistry*

Substances

Alkaloids
Pyrimidines
Sesquiterpenes