Sudden reversible pacemaker failure in a patient with cardiac sarcoidosis: an unfortunate case of ventricular septal pacing

Nobuhiro Takasugi; Tomoki Kubota; Itta Kawamura; Mieko Takasugi; Hiromitsu Kanamori; Hiroaki Ushikoshi; Arihiro Hattori; Takuma Aoyama; Masanori Kawasaki; Kazuhiko Nishigaki; Genzou Takemura; Shinya Minatoguchi

doi:10.1093/europace/eur435

Sudden reversible pacemaker failure in a patient with cardiac sarcoidosis: an unfortunate case of ventricular septal pacing

Europace. 2012 Jul;14(7):1061-2. doi: 10.1093/europace/eur435. Epub 2012 Jan 25.

Authors

Nobuhiro Takasugi¹, Tomoki Kubota, Itta Kawamura, Mieko Takasugi, Hiromitsu Kanamori, Hiroaki Ushikoshi, Arihiro Hattori, Takuma Aoyama, Masanori Kawasaki, Kazuhiko Nishigaki, Genzou Takemura, Shinya Minatoguchi

Affiliation

¹ Division of Cardiovascular Medicine, Department of Internal Medicine, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan. konezumi@ccn3.aitai.ne.jp

PMID: 22277641
DOI: 10.1093/europace/eur435

Abstract

We report a case of sudden marked deterioration of ventricular stimulation threshold resulting in pacemaker failure 16 months after a ventricular septal lead implantation for atrioventricular block. Echocardiography revealed septal wall thinning at the electrode-tissue interface, which was not detected pre-operatively. Endomyocardial biopsy confirmed cardiac sarcoidosis. The increased threshold was reversible with prednisolone.

Publication types

Case Reports

MeSH terms

Adult
Anti-Inflammatory Agents / therapeutic use
Atrioventricular Block / complications
Atrioventricular Block / prevention & control*
Cardiomyopathies / drug therapy*
Cardiomyopathies / etiology*
Humans
Male
Pacemaker, Artificial / adverse effects*
Prednisolone / therapeutic use*
Prosthesis Failure
Sarcoidosis / drug therapy*
Sarcoidosis / etiology*
Treatment Outcome
Ventricular Septum

Substances

Anti-Inflammatory Agents
Prednisolone