The utility of far-infrared illumination in oxygenation dynamics as measured with near-infrared spectroscopy

J Biophotonics. 2012 Oct;5(10):719-23. doi: 10.1002/jbio.201100108. Epub 2012 Jan 23.

Abstract

Near-infrared spectroscopy (NIRS) is a noninvasive method for measuring the oxygenation in muscle and other tissues in vivo. For quantitative NIRS measurement of oxygenation dynamics, the vessel-occlusion test was usually applied as physiological intervention. There are several drawbacks of the vessel-occlusion method that include skin contact, uncomfortable and microcirculation block of patients. Thus, we propose the far-infrared (FIR) illumination as a new physiological intervention method in this paper. Our preliminary result shows a linear correlation of oxygenation dynamic signals between FIR illumination and arterial-occlusion test (AOT) that implies the FIR illumination could be applied for hemodynamic response measurement in clinical diagnosis.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / metabolism
  • Cardiovascular System / metabolism
  • Hemoglobins / metabolism
  • Humans
  • Infrared Rays*
  • Oxygen / metabolism*
  • Spectroscopy, Near-Infrared*

Substances

  • Biomarkers
  • Hemoglobins
  • Oxygen