In vitro and ex vivo studies of antioxidant activity of carrageenans, sulfated polysaccharides from red algae

E V Sokolova; A O Barabanova; V A Homenko; T F Solov'eva; R N Bogdanovich; I M Yermak

doi:10.1007/s10517-011-1159-5

In vitro and ex vivo studies of antioxidant activity of carrageenans, sulfated polysaccharides from red algae

Bull Exp Biol Med. 2011 Feb;150(4):426-8. doi: 10.1007/s10517-011-1159-5.

Authors

E V Sokolova¹, A O Barabanova, V A Homenko, T F Solov'eva, R N Bogdanovich, I M Yermak

Affiliation

¹ Pacific Institute of Organic Biochemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.

PMID: 22268034
DOI: 10.1007/s10517-011-1159-5

Abstract

Antioxidant properties of structurally different sulfated polysaccharides (carrageenans) were studied in vitro and ex vivo. Ferric reducing antioxidant activity of carrageenans and their inhibitory effects on hydroxyl radicals and superoxide anion radicals were demonstrated in vitro. Activity of carrageenans depends on the polysaccharide structure. Carrageenans stimulate catalytic activity of SOD from donor erythrocyte.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antioxidants / chemistry
Antioxidants / pharmacology*
Carrageenan / chemistry
Carrageenan / pharmacology*
Erythrocytes / drug effects
Erythrocytes / enzymology
Free Radical Scavengers / chemistry
Free Radical Scavengers / pharmacology
Humans
Hydroxyl Radical / metabolism
Oxidation-Reduction
Plant Extracts / chemistry
Plant Extracts / pharmacology
Rhodophyta / chemistry*
Superoxide Dismutase / metabolism*
Superoxides / metabolism

Substances

Antioxidants
Free Radical Scavengers
Plant Extracts
Superoxides
Hydroxyl Radical
Carrageenan
Superoxide Dismutase