Gallbladder motility disorders estimated by non-invasive methods

Hepatogastroenterology. 2012 Jan-Feb;59(113):13-6. doi: 10.5754/hge11286.

Abstract

Background/aims: The aim is to compare the radionuclide (DC) and ultrasonographic (US) method in the assessment of gallbladder (GB) motility.

Methodology: The study was performed in 15 controls (C), 10 patients with acute cholecystitis (AC), 20 patients with chronic acalculous cholecystitis (CAC), 26 patients with chronic cholecystitis with calculosis (CCC) as well as in 15 patients with GB dyskinesia (D). GB emptying period (EP), ejection fraction (EF) and ejection rate (ER) were estimated with dynamic cholescintigraphy (DC) and US.

Results: The DC and US finding in the patients with AC was typical in all the patients, i.e. GB was not visualized at all on DC, while on US, stone was visible in the cystic duct. There were significant differences (p<0.05) between the EF and ER values obtained between C and the three groups of patients CAC, CCC and D, using both methods. However, there were no significant differences in EF, EP and ER values among CAC, CCC and D (p>0.05). There was also high correlation between the results obtained with both methods in all the groups of patients studied.

Conclusions: The results obtained by both methods are valuable for the assessment of GB motility. Although there are no significant differences and there is a high correlation between the values, radionuclide method is more precise, because it can register motility continuously.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acalculous Cholecystitis / diagnosis
  • Acalculous Cholecystitis / physiopathology
  • Adult
  • Aged
  • Biliary Dyskinesia / diagnosis
  • Biliary Dyskinesia / physiopathology
  • Cholecystitis, Acute / diagnosis
  • Cholecystitis, Acute / physiopathology
  • Chronic Disease
  • Diagnostic Techniques, Digestive System*
  • Female
  • Gallbladder / diagnostic imaging*
  • Gallbladder / physiopathology
  • Gallbladder Diseases / diagnosis*
  • Gallbladder Diseases / physiopathology
  • Gallbladder Emptying*
  • Humans
  • Lithiasis / diagnosis
  • Lithiasis / physiopathology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Radionuclide Imaging
  • Radiopharmaceuticals*
  • Serbia
  • Severity of Illness Index
  • Technetium Tc 99m Diethyl-iminodiacetic Acid*
  • Ultrasonography, Doppler, Color*
  • Young Adult

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Diethyl-iminodiacetic Acid