Spoligotyping of Mycobacterium africanum, Burkina Faso

Emerg Infect Dis. 2012 Jan;18(1):117-9. doi: 10.3201/eid1801.110275.

Abstract

Using Ziehl-Neelsen-positive slides collected from tuberculosis diagnostic centers in Burkina Faso, we showed that 20% of 80 spoligotyping-positive DNA samples had a characteristic Mycobacterium africanum-specific genomic signature. This result suggests that M. africanum is still present in Burkina Faso at almost the same prevalence as 15-20 years ago.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Typing Techniques
  • Burkina Faso / epidemiology
  • DNA, Bacterial / genetics
  • Genotype
  • Humans
  • Mycobacterium / classification*
  • Mycobacterium / genetics*
  • Mycobacterium Infections / epidemiology*
  • Mycobacterium Infections / microbiology*

Substances

  • DNA, Bacterial